L-ASPARTIC ACID

L-ASPARTIC ACID

PRODUCT IDENTIFICATION

CAS NO.

56-84-8

L-ASPARTIC ACID

EINECS NO. 200-291-6

FORMULA C₄H₇NO₄

MOL WT. 133.10

H.S. CODE

2922.49

TOXICITY

SYNONYMS 2-Aminobutanedioic acid; 2-aminosuccinic acid;

Asp; L-2-Aminobutanedioic acid; L-Aminosuccinic acid; L-Aspartic acid; (S)-(+)-Aspartic Acid; sparaginic Acid; (S)-Aminobutanedioic acid; L-(+)-Aspartic acid;

SMILES

CLASSIFICATION

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE

white crystals

MELTING POINT 270 - 271 C

BOILING POINT Decomposes (> 300 C)

SPECIFIC GRAVITY

1.66

SOLUBILITY IN WATER Slightly soluble (4g/l)

pH 2.5 - 3.5 (10% sol.)

VAPOR DENSITY

AUTOIGNITION

NFPA RATINGS

Health: 1; Flammability: 0; Reactivity: 0

REFRACTIVE INDEX

FLASH POINT

STABILITY

Stable under ordinary conditions. Moisture, light sensitive.

GENERAL DESCRIPTION

Amino Acid is any of the organic compounds in which one (or more ) amino group (-NH₂) and one (or more ) carboxylic acid group (-COOH) are both present with general formula R-CH(NH₂)COOH containing carbon, hydrogen, oxygen, nitrogen, and in certain cases sulfur atoms. Two groups attached to the same carbon (called the alpha-carbon atom at the end of the compound) are polymerized to form peptides and proteins. The amine group is protonated to form -NH₃⁺ at low pH. The carboxylic acid group is deprotonated to form -CO₂^- at high pH. The carbon atom in the carboxyl group of one amino acid binds covalently to the nitrogen atom in the amino group of another amino acid to form a peptide bond with the release of a water molecule. Proteins are synthesized through the covalent chemical polypeptide bonds. The sequence of these amino acids in the protein polypeptides determines the shape, properties, and hence biological role of the protein that function as chemical messengers and as intermediates in metabolism. Proteins are composed of various proportions of about 20 commonly occurring amino acids. Plants or other biological systems can synthesize amino acids from simple inorganic compounds, but animals rely on adequate supplies in their diet. More than 100 common amino acids occur in plants or in other microorganic systems. The 20 amino acids commonly found in animals are Alanine, Arginine, Asparagine, Aspartic Acid, Cysteine, Glutamic Acid, Glutamine, Glycine, Histidine, Isoleucine, Leucine, Lysine, Methionine, Phenylalanine, Proline, Serine, Threonine, Tryptophan, Tyrosine, and Valine. Many of the amino acids can be synthesized in the human or animal body from other cellular metabolites when needed (called Non-essential Amino Acids). Animals are not able to synthesize some amino acids necessary in metabolism in sufficient quantities. It must therefore be present in the diet (called Essential Amino Acids). In man, these essential amino acids are Arginine, Histidine, Isoleucine, Leucine, Lysine, Methionine, Phenylalanine, Threonine, Tryptophan and Valine. Aspartic acid is a Non-Essential Amino Acid having an acidic carboxyl group on its side chain which can serve as both an acceptor and a donor of ammonia. It is converted to L-Asparagine by binding with ammonia. It forms Carbamyl-L-Aspartic acid which roles purine as well as pyrimidine biosynthesis. It has been shown to occur in enzyme sites including pepsin.

SALES SPECIFICATION

APPEARANCE

white crystals

ASSAY

98.5 - 101.0%

SPECIFIC ROTATION

+24.5° ~ +25.8°

LOSS ON DRYING

0.2% max

RESIDUE ON IGNITION

0.1% max

CHLORIDE

0.02% max

SULFATE

0.03% max

HEAVY METALS

10ppm max

IRON

10ppm max

ARSENIC

1ppm max

AMMONIUM SALTS

0.02% max

TRANSPORTATION

PACKING

25kgs in fiber drum

HAZARD CLASS Not regulated

UN NO.

OTHER INFORMATION

Hazard Symbols: n/a, Risk Phrases: n/a, Safety Phrases:24/25

GENERAL PROPERTIES OF AMINO ACIDS

Amino Acid	Abbreviation		Formula (Mol WT)	pK₁	pK₂	pK_R	pI	Hydropathy Index
Amino Acid	3-Letters	1-Letter	Formula (Mol WT)	-COOH	-NH₃⁺	R group	pI	Hydropathy Index
Alanine	Ala	A	C₃H₇NO₂(89.09)	2.34	9.69	-	6.00	1.8
Arginine	Arg	R	C₆H₁₄N₄O₂(174.20)	2.17	9.04	12.48	10.76	-4.5
Asparagine	Asn	N	C₄H₈N₂O₃(132.12)	2.02	8.80	-	5.41	-3.5
Aspartic Acid	Asp	D	C₄H₇NO₄(133.10)	1.88	9.60	3.65	2.77	-3.5
Cysteine	Cys	C	C₃H₇NO₂S(240.30)	1.96	10.128	8.18	5.07	2.5
Glutamic Acid	Glu	E	C₅H₉NO₄(147.13)	2.19	9.67	4.25	3.22	-3.5
Glutamine	Gln	Q	C₅H₁₀N₂O₃(146.15)	2.17	9.13	-	5.65	-3.5
Glycine	Gly	G	C₂H₅O₂(75.07)	2.34	9.60	-	5.97	-0.4
Histidine	His	H	C₆H₉N₃O₂(155.16)	1.82	9.17	6.00	7.59	-3.2
Isoleucine	Ile	I	C₆H₁₃NO₂(131.18)	2.36	9.60	-	6.02	4.5
Leucine	Leu	L	C₆H₁₃NO₂(131.18)	2.36	9.60	-	5.98	3.8
Lysine	Lys	K	C₆H₁₄N₂O₂(146.19)	2.18	8.95	10.53	9.74	-3.9
Methionine	Met	M	C₅H₁₁NO₂S(149.21)	2.28	9.21	-	5.74	1.9
Phenylalanine	Phe	F	C₉H₁₁NO₂(165.19)	1.83	9.13	-	5.48	2.8
Proline	Pro	P	C₅H₉NO₂(115.13)	1.99	10.60	-	6.30	1.6
Serine	Ser	S	C₃H₇NO₃(105.19)	2.21	9.15	-	5.58	-0.8
Threonine	Thr	T	C₄H₉NO₃(119.12)	2.09	9.10	-	5.60	-0.7
Tryptophan	Trp	W	C₁₁H₁₀N₂O₂(204.23)	2.83	9.39	-	5.89	-0.9
Tyrosine	Tyr	Y	C₉H₁₁NO₃(181.19)	2.20	9.11	10.07	5.66	-1.3
Valine	Val	V	C₅H₁₁NO₂(117.15)	2.32	9.62	-	5.96	4.2